摘要
目的通过经直肠前列腺穿刺前后血清PSA水平的检测，观察其对血清PSA水平的影响时间。方法应用放射免疫分析检测方法，对前列腺穿刺前后20例患者的血清PSA（T-PSA、F-PSA）进行检测，并计算出F／T值。对所得资料进行统计学处理，观察去除影响因素后血清PSA回落到操作前水平的时间。结果20例患者行经直肠前列腺穿刺活检前FPSA、TPSA及F／T值分别为：1．9722．986、15．976±3．986、0．1061±0．824；检查后30—60min值分别为：20．945±-5．765、34．765±5．812、0．6024±0．521；明显高于活检前，与活检前相比差异具有显著性意义（P〈0．01）。检查后24h值分别为：18．796±4．976、32．654±5．624、0．5754±0．624；与活检前相比差异具有显著性意义（P〈0．01）。检查后2周值分别为：14．159±65、27．541±4。824、0．4942±0．497；与活检前相比差异具有显著性意义（P〈0．01）。检查后4周值分别为：10．925±3．926、22．904±4．596、0．4669±0．824；与活检前相比差异具有显著性意义（P〈0．01）。检查后6周值分别为：3．976．±3．502、16．864±3．024、0．3215±0．423；与活检前相比差异仍具有显著性意义（P〈0．05）。检查后8周值分别为：1．824±3．271、16．021±2．91、0．1288±0．497；与活检前相比差异无统计学意义（P〉0．05）。结论前列腺穿刺活检（经直肠）可使血清PSA水平明显升高，30～60min达到高峰，升高持续时间超过6周，8周后基本恢复到检查前水平。
Objective To oberserve the Transrectal-protate-needle-biopsy impacts on serum level of PSA through the measurement of serum concentration of PSA before and after transrectal protate needle biopsy while being daily. Methods Use the immunity of radiating to analyse the detection method, to examine serum concentration of PSA（ TPSA, FPSA）of patient of 20 cases before and after Transrectal protate needle biopsy, cal- culate out F/T value. Carry on statistics deal with to income materials, to oberserve the serum PSA fall back to time of the level before operating after getting rid of the influence factor clearly. Results FPSA, TPSA and F/T value before being examine in patients in 20 cases including ： 1. 972 ± 2. 986,15. 976 ± 3. 986,0. 1061 ± 0. 824; After 30 ± 60 minutes value including： 20. 945 ± 5. 765,34. 765 ± 5. 812,0. 6024 ± 0. 521 ; Obviously higher than them before examining, compare the difference before examining with living and have significance meanings （ P 〈 0.01 ）. After 24 hours value including ： 18. 796 ± 4. 976,32. 654 ± 5. 624,0. 5754 ± 0. 624 ; Compare the difference before examining with living and have significance meanings （ P 〈 0. O1 ）. After 2 weeks value inclu- ding： 14. 159 ±4. 865,27. 541 ± 4. 824,0. 4942 ± 0. 497 ; Compare the difference before examining with living and have significance meanings （ P 〈 O. 01 ） ： After 4 weeks value including ： 10. 925 ± 3. 926,22. 904 ± 4. 596, 0. 4669 ± 0. 824 ; Compare the difference before examining with living and have significance meanings （ P 〈 0. 01 ）. After 6 weeks value including ：3. 976 ± 3. 502,16. 864 ± 3. 024,0. 3215 ± 0. 423 ; Compare the difference before examining with living and still have a significance meaning（ P 〈 0.05 ）. After 8 weeks value including： 1. 824 ± 3. 271,16. 021 -± 2. 91,0. 1288 ± 0. 497;Do not also have a statistics meaning to compare the differ- ence before examining with living（ P 〉 0. 05 ）. Conclusion Transreetal prostate needle biopsy could
出处
《中国临床实用医学》
2008年第9期18-19,共2页
China Clinical Practical Medicine
