摘要
利多卡因广泛应用于局部神经阻滞和抗心律失常,后来许多实验证实利多卡因能抑制中性粒细胞炎性反应,抑制肺泡Ⅱ型上皮细胞(AT-Ⅱ)过度凋亡和坏死,减轻多种原因引起的急性肺损伤。本文就有关利多卡因对急性肺损伤的作用及机制的研究报道进行了综述。
Lidocaine is widely used in regional nerve block and anti-arrhythmia,later, many experiments have shown that lidocaine can inhibit the inflammatory reaction of neutrophil. inhibit excessive apoptosis and necrosis of alveolar type Ⅱ cells （AT-Ⅱ ） ,reduce acute lung injury caused by various reasons. This article describes the role of lidocaine on acute lung injury and its mechanisms.
出处
《医学综述》
2008年第18期2792-2794,共3页
Medical Recapitulate
基金
湖南省教育厅2006年科学研究项目
