摘要
目的提高对艾滋病合并马尔尼菲青霉病的认识。方法回顾1例艾滋病合并马尔尼菲青霉病病例的临床病理资料并文献复习。结果艾滋病合并马尔尼菲青霉病以发热、咳嗽为主要症状,相对特异的临床表现为皮肤出现中心坏死性脐状丘疹,抗炎或抗结核治疗无效,白细胞计数多正常或偏低,真菌培养和病理活检可确诊。结论艾滋病合并马尔尼菲青霉病误诊率高,常进展为播散型感染。对于长期发热、咳嗽,抗炎或抗结核治疗无效,白细胞比值正常或偏低的患者应考虑此病的可能。
Objective To improve the degree of acquaitance to acquired immunodeficiency syndrome （AIDS） associated Penicilliosis marneffei （PSM）. Methods The clinicopathologic data were reviewed in one case of AIDS associated PSM and related literature. Results Most common clinical presentations were observed in patients, including fever and cough. Specific finding was papules with central necrotic umbilication. Antibiotic or anti-tuberculosis treatment was ineffective. Most of patients were normal or decreased in white blood cell counts. PSM could be, diagnosed by fungal culture, and histopathological examination. Conclusions AIDS associated PSM always develop disseminated infection with a high rate of misdiagnosis. When the patients present fever and cough, but the symptoms are not improved by antibiotic or anti-tuberculosis treatment and white blood cell counts were normal or decreassed, we should consider the possibility of AIDS associated PSM.
出处
《诊断病理学杂志》
CSCD
2008年第4期287-289,共3页
Chinese Journal of Diagnostic Pathology
关键词
艾滋病
马尔尼菲青霉病
诊断
Acquired immunodeficiency syndrome
Penicilliosis marneffei
Diagnosis
