摘要
活性氧信号和钙信号广泛存在于机体内,两者相互作用,共同参与调节机体多种生理功能及病理过程。本文对这两个信号系统之间的相互作用及相关机制、在心力衰竭过程中的作用及可能的临床应用前景进行了综述。
Reactive oxygen species （ROS） and calcium signal constitute the most important intracellular signaling systems that participate in the regulation of multitude cellular functions. Here we briefly review interactions between the two prominent signaling systems, their integrated effects on heart failure, and their potentials for therapeutic interventions.
出处
《生命科学》
CSCD
2008年第4期528-539,共12页
Chinese Bulletin of Life Sciences
基金
国家自然科学基金(30630021
30770870
30500182)
"973"计划(2007CB512100)
关键词
活性氧
钙
心力衰竭
reactive oxygen species
calcium
heart failure
