摘要
骨关节病是一种对人体健康和生活影响较大的疾病,但不同的发病部位又各具其自身特点。迄今,骨关节病的病因和病理机制还不甚清楚。近年来,有关不同部位骨关节病软骨细胞程序性细胞死亡的研究已成为热点。下面就近年来有关颞下颌关节骨关节病软骨细胞的程序性细胞死亡特点,与骨关节病软骨细胞程序性细胞死亡有关的主要信号转导途径及其影响因素的研究进展作一综述。
Osteoarthrosis (OA) is harmful to health and daily life, but its features varied among different joints. The etiopathogenisis and pathomechanism of OA is still unclear. In recent there have been many reports on the chondrocyte apoptosis of osteoarthrosis in different joints. In the present review the recent study on the features of chondrocyte apoptosis, the associated signal transduction pathway and influential factor in OA are provided.
出处
《国际口腔医学杂志》
CAS
2008年第3期271-273,282,共4页
International Journal of Stomatology
基金
国家自然科学基金资助项目(30471909
30772429)