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慢性肾功能不全患者血清同型半胱氨酸和白细胞介素6的变化及意义 被引量:4

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摘要 目的:观察慢性肾功能不全患者病情发展中同型半胱氨酸(HCY)和白细胞介素6(IL-6)的变化,探讨二者联合检测对于观察慢性肾功能不全发展的临床应用价值。方法:采取酶联免疫吸附法测IL-6,循环酶法测HCY,检测41例慢性肾功能不全患者(慢性肾功能不全组)血清中HCY及IL-6值,并设50例体检合格的健康者为健康对照组。结果:慢性肾功能不全组的HCY、IL-6明显高于健康对照组(P<0.01),且慢性肾功能不全组HCY、IL-6值与肌酐(Cr)值呈正相关。结论:慢性肾功能不全患者血清中HCY、IL-6值明显升高,且随着病情发展及Cr的升高,HCY、IL-6也持续升高。二者联合检测对于观察慢性肾功能不全患者病情的发展变化具有重要价值。
出处 《实用医学杂志》 CAS 2008年第16期2811-2812,共2页 The Journal of Practical Medicine
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