摘要
为进一步研究对幽门螺杆菌(HP)具有较高根治率且对胃粘膜病变具有治疗作用的药物疗法,将87例HP阳性慢性胃炎患者随机分为3组,分别以灭HP胶囊、灭HP胶囊结合低剂量三联和低剂量三联疗法治疗。结果,灭HP胶囊HP根治率为80.0%,与低剂量三联组(83.3%)相当;而灭HP胶囊结合低剂量三联组为97.4%(P<0.05),且对胃粘膜活动性炎症有明显治疗作用(P<0.01),对伴肠上皮化生的慢性萎缩性病变也具有一定作用(P<0.05)。
87 chronic gastritis with HP-positive were randomly divided into three groups and treated respectively with ①Low-dose standard triple therapy (LSTT) ;②the decoction of killing HP (DKHP), and DKHP+ LSTT. The results showed that the HP eradication rate in DKHP (80. 0% ) was commensurated with that of LSTT (83. 3% ), but in DKHP+LSTT was 97. 4%,significantly higher than that of other two groups (P <0. 05). After HP eradicated the mucosal inflammation, stasis and some atrophy lesions were also improved significantly (P<0.01, <0.05). It is suggested that DKHP combined with LSTT may not only have high HP-eradication,but have some therapeutic effect for atrophic lesions of gastric mucose.
关键词
胃炎
幽门螺杆菌
胶囊
低剂量
三联疗法
Helicobacter pylori
the decoction of killing Helecobacter pylori
gastritis
mucosa