摘要
目的探讨多发性硬化(MS)患者血清尿酸(UA)水平及其临床意义。方法采用酶定量分析法对65例MS患者和60例非炎症性神经系统疾病患者的尿酸水平进行检测。结果MS组血清UA水平明显低于对照组,两者相比差异有显著性(P<0.01);女性患者尿酸水平低于男性患者(P<0.05);且MS组病程越长,血清UA水平越低(P<0.05)结论MS患者血清UA水平降低,且与性别、病程相关。
Objective To explore the serum levels of uric acid in multiple sclerosis patients and its clinical significance Methods A quantitative enzymatic assay according to the manufacturers protocol was adopted to detect serum UA levels in 65patients with MS ad 50 patients with non - inflammatory neurological disease Results The mean serum UA level in patients with MS was significantly lower in comparison with controls （ P 〈 0.01 ） ; and mean serum UA level of female MS patients was lower than that of male MS patients （ P 〈 0.05 ） ; the longer clinical course, mean serum UA level was lower （ P 〈 0.05 ） Conclusion The serum UA level in MS patient is low and it is related to gender and clinical course.
出处
《安徽医学》
2008年第5期540-541,共2页
Anhui Medical Journal
