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聚合酶链反应及抗体检测对单纯疱疹病毒性脑炎早期诊断的意义 被引量:1

Significance of PCR to detect gene DNA and ELISA to detect specific antibody IgG for rapid diagnosis of herpes simplex encephalitis.
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摘要 通过特异性抗体(ELISA)及聚合酶链反应(PCR)检测,38例散发性脑炎中18例诊断为单纯疱疹病毒性脑炎(HSE),20例为非HSE的散发性脑炎(NHSSE)。并与30例其它神经系统疾病患者作三组对比性临床及实验室研究,发现HSE在临床表现、脑脊液、头颅CT等方面有其特征性。18例HSE的24份脑脊液(CSF)标本中,PCR阳性18份,IgG阳性19份,其中13份PCR和IgG皆阳性;其余两组PCR和IgG均阴性。PCR和IgG检测有可能成为HSE常规诊断方法,PCR于发病当天即可获得诊断。
出处 《中华神经科杂志》 CAS CSCD 1994年第4期239-242,共4页 Chinese Journal of Neurology
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