摘要
目的通过分析593例住院患者抗菌药物的应用情况以及药物不良反应(ADR),了解我院抗生素应用的合理性,探讨ADR的发生规律,为临床用药及ADR的预防提供科学依据。方法采用回顾性调查方法,对我院2006年7月-2007年7月住院病例中抗菌药物使用种类、使用频度(DDDs)、药物利用指数(DUI)、联合用药情况以及ADR在性别、年龄之间的差异进行统计分析。结果共涉及10种抗菌药物,以头孢曲松钠使用频度最高,所有药品的DUI<1。抗菌药物单用比例为75.80%。我院ADR发生率女性显著高于男性,老年人群显著高于青壮年,两者之间有显著性差异(P<0.05)。结论我院抗菌药物的应用基本合理。医务工作者应进一步加强对ADR的认识,以促进临床合理用药。
Objective Application of antibacterials and correlation factors of ADR in 593 inpatients were analyzed,rationality of antibacterial use and ADR＇s regularity were explored.Methods By retrospective study,authors surveyed the category of antibacterials,DDDs,DUI,combined medication,the differences of ADR between males and females or different ages of inpatients from July 2006 to July 2007.Results 10 antibacterials were used,ceftriaxone sodium was used most frequently,and DUIs〈1.Single use of drug was 75.80%.There were significant differences in the incidence of ADR between males and females or different ages（P〈0.05）.Conclusion Application of antibacterials in our hospital is mainly reasonable,and medical workers should realize the regularities of ADR further,and prompt the rational medication.
出处
《实用药物与临床》
CAS
2008年第4期226-227,共2页
Practical Pharmacy and Clinical Remedies
