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左氧氟沙星致腹水 被引量:12

Levofloxacin-associated ascites
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摘要 A 23-year-old man complained of headache, sore throat and fever for 2 days and was diagnosed as upper respiratory tract infection in a clinic. The patient developed nausea, abdominal distension, abdominal pain and diarrhea after receiving intravenous infusion of levofloxacin 200mg. Physical examination showed abdominal muscular tension, abdominal tenderness and positive shifting dullness while ultrasound suggested ascites.His symptoms were resolved after stopping the medication and taking dexamethasone 15mg. No abnormality on abdomen was found by ultrasound. Six months later, the same symptoms were recurred after intravenous infusion of levofloxacin 200mg and returned to normal gradually after withdrawal of levofloxacin and start of the same therapy. It is considered that ascites is associated with levofloxacin. A 23-year-old man complained of headache, sore throat and fever for 2 days and was diagnosed as upper respiratory tract infection in a clinic. The patient developed nausea, abdominal distension, abdominal pain and diarrhea after receiving intravenous infusion of levofloxacin 200mg. Physical examination showed abdominal muscular tension, abdominal tenderness and positive shifting dullness while ultrasound suggested ascites.His symptoms were resolved after stopping the medication and taking dexamethasone 15mg. No abnormality on abdomen was found by ultrasound. Six months later, the same symptoms were recurred after intravenous infusion of levofloxacin 200mg and returned to normal gradually after withdrawal of levofloxacin and start of the same therapy. It is considered that ascites is associated with levofloxacin.
作者 吴霞
出处 《药物不良反应杂志》 2004年第6期407-408,共2页 Adverse Drug Reactions Journal
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