摘要
目的研究中药对自然周期冻融胚胎移植(frozen embryo transfer,FET)的临床妊娠率和种植率的影响。方法在已有冷冻胚胎拟做冻融胚胎移植的患者中,选择自然周期有排卵的患者,在胚胎移植当月,设立单纯西药者作为对照组,同时加用中药为治疗组,观察两组间的临床妊娠率、种植率、移植日子宫内膜厚度、移植后2周血清雌激素(E2)水平、孕激素(P4)水平。结果治疗组的临床妊娠率(47.37%,36/76例)及种植率(22.38%,47/210个胚胎)高于对照组〔32.14%(54/168例),16.09%(74/460个胚胎),P<0.05〕;子宫内膜厚度、E2和P4两组间比较差异无统计学意义(P>0.05)。结论中药在自然周期FET中对提高临床妊娠率和种植率有一定作用。
Objective To study the effect of Chinese herbal medicine on the clinical pregnancy rate and implantation rate of frozen embryo transfer （FET） in a natural cycle. Methods Women with frozen embryos planned to receive FET and had spontaneous ovulation in a natural cycle were chosen for observation. They were assigned to the treated group and the control group, both were treated with conventional medicine in the very month of FET, but to the treated group, Chinese herbal medicine was given additionally. The clinical pregnant rate, implantation rate, endometrial thickness during transferring, as well as the levels of estrogen and progesterone 2 weeks after transfer in the two groups were observed and compared. Results The clinical pregnancy rate and implantation rate in the treated group were significant higher than those in the control group, 47.37% （36/76 cases） vs 32.14% （54/168 cases） and 22.38% （47/210 embryos） vs 16. 09% （74/460 embryos）, respectively （ all P 〈 0. 05 ）. Difference between the two groups in endometrial thickness, levels of estrogen and progesterone showed no statistical significance （P 〉0. 05）. Conclusion Chinese herbal medicine could enhance the clinical pregnancy rate and implantation rate in the natural cycle of FET to certain extent.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2008年第7期591-593,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
冻融胚胎移植
中药
临床妊娠率
frozen embryo transfer
Chinese herbal medicine
clinical pregnancy rate
