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蛋白质β-发夹模体片断的识别 被引量：3

RECOGNITION OF β-HAIRPIN MOTIFS IN PROTEINS
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摘要 依据β-发夹氨基酸序列中的保守性特征,分别以氨基酸(20种氨基酸和一个空位)和氨基酸紧邻关联为参数,通过构建位置权重矩阵和选取氨基酸最佳序列模式片断,利用相似性打分函数,对蛋白质超二级结构β-发夹模体片断进行识别,获得了较好的预测效果. Based on the conservative performance of amino acid sequence,prediction of β-hairpin motifs in supersecondary protein structure is made. Amino acid composition and dipeptide composition are taken as parameters. Position weight matrix is constructed and optimal sequence pattern segment is selected. Then, by use of similarity scoring function,β-hairpin motifs of supersecondary protein structure are recognized. The prediction results turn out to be quite satisfactory.
作者 姜雪 胡秀珍
机构地区 内蒙古工业大学理学院
出处 《内蒙古工业大学学报（自然科学版）》 2008年第2期88-94,共7页 Journal of Inner Mongolia University of Technology：Natural Science Edition
基金 内蒙古自然科学基金资助项目200508010509
关键词 Β-发夹模体 位置权重矩阵 相似性打分函数 域值 β-hairpin motif position weight matrix similarity scoring function cut-off
分类号 Q61 [生物学—生物物理学]
  • 相关文献

参考文献15

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二级参考文献18

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共引文献15

同被引文献18

  • 1施建宇,潘泉,张绍武,梁彦.基于支持向量机融合网络的蛋白质折叠子识别研究[J].生物化学与生物物理进展,2006,33(2):155-162. 被引量：19
  • 2杨科利,李前忠,林昊.预测酵母(Yeast)基因转录因子结合位点[J].内蒙古大学学报（自然科学版）,2006,37(5):524-530. 被引量：16
  • 3胡秀珍,李前忠.用离散量的方法识别蛋白质的超二级结构[J].生物物理学报,2006,22(6):424-428. 被引量：16
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  • 7Kumar M,Bhasin M,Natt N K,et al.BhairPred:prediction of b-hairpins in a protein from multiple alignment information using ANN and SVM techniques[J].Nucleic Acids Research,2005,33:154-159. 被引量：1
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引证文献3

二级引证文献3

内蒙古工业大学学报（自然科学版）
2008年 第2期

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