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64层螺旋CT在不同心率情况下对不同直径冠状动脉测量准确性的评价--心脏体模模拟实验

Accuracy and influence of different heart rate on measuring different coronary artery with 64-slice spiral CT using a pulsating cardiac phantom
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摘要 目的采用Osiris419软件和AW4.2工作站心脏软件包对不同心率情况下心脏体模中不同直径模拟冠状动脉进行测量,比较两种测量方法对管腔测量的准确性。方法运用GELightSpeed64层螺旋CT,以心脏扫描的模式对心脏动态体模进行扫描。心率设置为0、40、45、50、55、60、65、70、75、80、85、90、95、100、105次/min。X线管转速为0.35s。对所有扫描图像在R-R间期90%进行双扇区重组,对重建图像进行容积重组(VR)。第一步,运用Osiris419软件,分别对4.2mm、2.3mm、2.0mm、1.6mm管径的模拟血管图像进行分析,得到关于管腔直径的一系列数值。第二步,将心脏体模中的同一组模拟冠状动脉图像在AW4.2工作站上采用CT心脏软件包进行测量,得到管腔值。结果随着心率增加,重组图像质量逐渐下降,运用Osiris419软件测得管腔值似有呈递增趋势。应用单因素方差分析发现心率对管径为4.2mm、2.3mm、2.0mm、1.6mm的冠状动脉采用Osiris419软件测量时的影响无统计学意义(P>0.05)。运用AW4.2工作站心脏分析软件包进行管腔直径的测量时,其测量值受心率的影响较大,数据无规律性,数据的差距较大。应用单因素方差分析发现心率对管径为4.2mm管腔应用心脏软件包测量时的影响无统计学意义(P=0.372),心率对管径为2.3mm、2.0mm、1.6mm的管腔测量时的影响有明显统计学意义(P=0.000)。将Osiris419软件与AW4.2工作站的心脏软件包中的测量方法测得的管腔值进行配对样本t检验,发现二种测量方法间的差异有显著性意义(P=0.028,P=0.000)。Osiris419软件测量较AW4.2工作站的心脏软件包中的测量准确性好。结论采用Osiris419软件评价心脏动态体模中不同管腔时,其测量值受心率影响较小,可较准确的测量管腔直径,更具有客观性,能够为临床的应用和基础研究提供帮助。运用AW4.2工作站的心脏分析软件包进行管腔直径的测量时,受心率的影响较� Objective To explore the accuracy and influence of different heart rate on measuring coronary artery with 64-detector row helical CT in using Osiris419 software and the heart package of measuring diameter value in AW4.2 in a pulsating cardiac phantom.Methods An adjustable pulsating cardiac phantom(GE)was scanned using a 40 mm VCT(GE Light Speed CT)with cardiac pulsating rates of 0,40,45,50,55,60,65,70,75,80,85,90,95,100 and 105 beats per minute(bpm).The variable rotation speeds technique of 0.35 s was used.The raw data were reconstructed using two-sector reconstruction algorithm at 90% R-R interval.First the images of coronary artery were evaluated using Osiris419 software.Then these images were evaluated by the heart package of measuring diameter value in AW4.2.Results Picture quality cut down and the caliber became bigger with the heart rate speeding up by Osiris419 software.By using one-factor analysis of variance,we can conclude that heart rate plays no statistical significance in measuring coronary artery of 4.2 mm,2.3 mm,2.0 mm,1.6 mm by Osiris419 software(P〉0.05).With the heart package of measuring diameter value in AW4.2,picture quality cut down obviously and the caliber became no regularity.By using one-factor analysis of variance,we can conclude that heart rate plays statistical significance in measuring coronary artery of 2.3 mm,2.0 mm,1.6 mm(P=0.000)and heart rate plays no significance in measuring coronary artery of 4.2 mm(P=0.372).By using paired samples test we can conclude that significance exists between the two methods and the method of Osiris419 surpasses the other one.Conclusion With Osiris419 software the measured values can relate less with heart rate.It can raise accuracy and plays more objectivity using Osiris419 software in a pulsating cardiac phantom to evaluate diameter of different coronary artery.It plays an important role in clinical research and application.By the heart package of measuring diameter value in AW4.2 the measured values relate more with heart
出处 《中国医学影像技术》 CSCD 北大核心 2008年第6期848-851,共4页 Chinese Journal of Medical Imaging Technology
关键词 冠状动脉 体层摄影术 X线计算机 心率 测量 心脏动态体模 Coronary artery,Tomography,X-ray computed,Heart rate,Measurement,Cardiac phantom
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