高频振荡通气治疗新生儿呼吸窘迫综合征的安全性分析被引量：31

The safety analysis of high-frequency oscillatory ventilation for neonatal respiratory distress syndrome

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摘要目的综合比较高频振荡通气(HFOV)与传统机械通气(CMV)对新生儿呼吸窘迫综合征(RDS)的安全性及潜在危害性。方法通过数据库检索出符合纳入分析条件的相关文献14篇,采用meta分析方法进行定性、定量综合分析,得出合并OR值及其95%可信区间。结果与CMV相比,HFOV可以降低RDS患儿慢性肺部疾病(CLD)的发生率(P=0.007),但增加新生儿脑室内出血(IVH)的危险性(P<0.05);两通通气方式引起的气漏、动脉导管重新开放、坏死性小肠结肠炎、早产儿视网膜病和脑白质软化方面差异无统计学意义(P>0.05)。结论与CMV相比,应用HFOV治疗新生儿呼吸窘迫综合征可减少CLD的发生,但增加重度IVH发生的危险性。

作者刘志军李思涛郝虎罗立倩肖昕

机构地区广东省广州市花都区人民医院儿科中山大学附属第六医院围产医学中心暨南大学附属第一医院新生儿科

出处《临床儿科杂志》 CAS CSCD 北大核心 2008年第3期191-194,共4页 Journal of Clinical Pediatrics

关键词高频振荡通气传统机械通气新生儿呼吸窘迫综合征 META分析 high frequency oscillatory ventilation conventional mechanical ventilation neonate respiratorydistress syndrome meta analysis

分类号 R722.1 [医药卫生—儿科]

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