摘要
目的:观察依达拉奉与降纤酶联合治疗急性脑梗死的疗效及安全性。方法:将50例急性脑梗死患者给予依达拉奉联合降纤酶(联合组)治疗,并与单纯应用降纤酶(降纤酶组)和血栓通注射液(血栓通组)治疗的患者分别在治疗第5、10、25d观察疗效。结果:治疗后联合组显效率(74%)明显优于血栓通组(34%)和降纤酶组(30%)(均P<0.01);神经功能缺损程度评分(NDS)减分幅度与降纤酶组相比(P<0.05)和血栓通相比(P<0.01),差异均有显著性。结论:依达拉奉联合降纤酶治疗急性脑梗死能明显提高显效率,改善神经功能,是治疗急性脑梗死的安全有效的方法之一。
Objective：To observe the efficacy and safety of edaravone joint defibrase in treatment of acute cerebral infarction. Methods： 50 patients wifh acute cerebral infarction were received intravenous infusion of edaravone and defibrase （joint group） , and the patients who were treated wifh defibrase（ defibrase group） ,and xueshuantong injection （xueshuantong group）sinplely, observed the efficacy on the 5,10,25d respectively. Results： The significant efficiency（74% ）was superior than the xueshuantong group（34% ）and than the defibrase group（30% ）（ P〈 0. 01 ） ; the difference of the reduction rate of the Nerve function edfeet score（NDS） was siginificant than tire defibrase group（ P 〈 0. 05 ）and the xueshuantong troup （P 〈 0. 01 ）. Conclusion： Edaravone joint defibrase treatment of acute cerebral infarction can improve the efficiency signifcant obviously and it can be improve the neurological function ,So it was an effective and safe methods im the treatment of acute cerebral infarction.
出处
《中国医药导刊》
2008年第3期395-396,共2页
Chinese Journal of Medicinal Guide
关键词
依达拉奉
降纤酶
急性脑梗死
安全性
Edaravone
Defibrase
Acute cerebral infarction
Safety
