摘要
目的研究不同强度芒刺负静电场（PNESF）作用对腹水瘤小鼠生存状况和生存期的影响。方法采用不同强度PNESF对小鼠进行全身作用，观测小鼠进食情况、体重变化和生存期，采用直线拟合方法作图分析。结果①电场作用期间，17kV和23kV组小鼠体重增加较大，拟合直线斜率分别为1．58和1．55；②停止电场作用之后，各实验组小鼠体重增长较电场处理期间减慢，其中17kV组小鼠体重增长慢于对照组，拟合直线斜率为0．80，而23kV组小鼠体重增长领先于其他实验组，拟和直线斜率达到1．28；③17kV组小鼠存活时间最长，生命延长率较对照组提高了25．53％。结论适当强度PNESF可有效提高腹水瘤小鼠的生存期。
Objective To study the effects of PNESF at different voltages on the life spans of aseites tumor bearing mice. Methods Forty aseites tumor bearing mice were divided into 5 groups and exposed to PNESF at 0, 10, 17, 23 and 30 kV, respectively, for 30 minutes daily on 4 successive days. All of the animals then received rou- tine care until death. Their eating habits, body weights and life spans were observed. A straight line fitting method was used for statistical analysis. Results The body weights of the mice exposed to 17 kV and 23 kV PNESF increased quickly during the four days of PNESF exposure. The weight gain in all groups declined after PNESF exposure was stopped. Thereafter the body weights of the mice exposed to the 17 kV PNESF increased more slowly than those in the control group. The mice exposed to the 23 kV PNESF gained weight more quickly than other groups. The mice exposed to the 17 kV PNESF lived the longest, demonstrating a lengthening of life of 25.5% compared with the control group. Conclusion Exposure to a PNESF of appropriate intensity might significantly increase the life span of aseites tumor bearing mice.
出处
《中华物理医学与康复杂志》
CAS
CSCD
北大核心
2008年第5期299-302,共4页
Chinese Journal of Physical Medicine and Rehabilitation
基金
吉林省科技厅科技发展计划项目资助课题（20030543-3）
教育部留学回国人员科研启动基金项目（2002）
关键词
芒刺负静电场
腹水瘤
生存期
Electrostatic field
Aseites tumors
Life span
