摘要
目的:探讨角膜移植术后泪膜功能的变化以及角膜知觉的恢复。方法:对23例患者24眼角膜移植术后1,2,3wk;1,2,3mo;1a的随访,检测泪液分泌量、泪膜破裂时间和角膜知觉。其中泪液分泌量采用Schirmer试验I检测,泪膜破裂时间采用KEELER泪膜镜测定非侵入性泪膜破裂时间(NiBUT)评价,角膜知觉采用Cochet Bonnet角膜知觉计测定。结果:角膜知觉与泪膜破裂时间在术后2mo以上开始逐渐恢复,而泪液分泌量在术后逐渐下降至稳定水平。结论:角膜移植术后角膜知觉泪膜破裂时间的恢复需要3mo^1a,甚至更长的时间,且二者呈正相关。角膜移植术后早期泪液分泌增多与局部炎症反应有关,随着炎症反应消退渐趋稳定。角膜移植术后应及时应用人工泪液成分滴眼液,缓解患者的干眼症状,保护角膜植片。
AIM： To observe the changes of tear-film function and corReal sensitivity after keratoplasty.
METHODS： Twenty-three cases （24 eyes） who was healthy and had same blood group received fresh （isolated time 〈 8 hours ） cornea from the supplier. During the follow-up （1, 2, 3 weeks, 1, 2, 3 months, 1 year）, tears secretion was measured by Shirmer Test I, tear film break-up time was detected by KEELER tear-film microscopy, corneal sensitivity was determined by Cochet Bonnet aesthesiometer.
RESULTS： Corneal sensitivity and BUT get resume 2 months after keratoplasty. The high tear secretion was stable after local stimulation was eliminated.
CONCLUSION ： It needs 3 months to 1 year or more time to make corneal sensitivity and BUT resume. And they are correlative. The high tear secretion in early stage after operation may concerned with local stimulation. And it will be stable after local stimulation is eliminated.
出处
《国际眼科杂志》
CAS
2008年第6期1200-1202,共3页
International Eye Science
关键词
角膜移植
泪膜
角膜知觉
随访研究
keratoplasty
tear film
corneal sensitivity
follow-up studies
