摘要
目的:探讨急性一氧化碳中毒后迟发性脑病(DEACMP)患者的头颅磁共振成像特点和诊断价值。方法:分析32例DEACMP患者的临床表现、头颅MRI资料。结果:DEACMP患者的主要临床表现为智能、人格改变;头颅MRI表现可分为3型:(1)神经核团受累型;(2)脑白质受累型;(3)皮层受累型。MRI特征:苍白球为对称性的卵圆形长T1、长T2信号,皮层下白质为对称性的弥漫、模糊云雾状长T1、长T2信号,侧脑室周围、半卵圆中心白质亦为对称云絮状长T1、长T2信号,胼胝体常受累。MRI显示苍白球合并脑白质受累者及皮层受累者,临床表现较重。结论:本病的诊断主要依靠病史、临床表现和头颅磁共振改变。
Objective：To investigrate the features and diagnostic value of MRI in delayed eneephalopathy after acute carbon monoxide poisoning （DEACMP）.Methods：The clinical manifestations and skull MRI data in 32 patients with DEACMP were analysed retrospectively.Results：The main clinical manifestations of this disease were intellectual disturbance and personality disorder.On the skull MRI findings,DEACMP was classified into three types.The MRI in type I showed neural nuclei involvement;the MRI in type 2 showed white matter of brain involvement and type 3 brain cortex involvement.The MRI characteristic signs deinostrated symmetric oval long T1 and long T2. signal intensity loci in bilateral globus pallidus, and symmetric diffuse cloudy and blurred lesions of long T1 and long T2 signal intensity appeared in the subcortical white matters of the centrum semiovale and also those surrounding both lateral ventricles.Corpus callosum was often involved.The clinical manifestations were more serious in those cases that multiple involvements of the globus pallidus complicated with white matter and cortex impairment occurred.Conclusion：The diagnosis of DEACMP mainly depends on case history, clinical manifestations and MRI features.
出处
《现代医药卫生》
2008年第13期1917-1919,共3页
Journal of Modern Medicine & Health
关键词
急性-氧化碳中毒
迟发性脑病
磁共振成像
Acute carbon monoxide poisoning
Delayed encephalopathy
Magnetic resonance imaging
