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脑梗死急性期血清白介素-6的变化及其临床意义 被引量:2

Change of serum interleukin-6 in patients with acute cerebral infarction and its significance
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摘要 目的:探讨急性脑梗死患者血清白介素-6(IL-6)水平的变化及其与脑梗死严重程度的关系。方法:测定63例急性脑梗死患者和24名健康人的血清IL-6的含量,按脑卒中患者临床神经功能缺损程度评分(NDS)标准对患者进行评分,分组比较。结果:脑梗死组血清IL-6水平明显高于正常对照组(P<0.01)。脑梗死重型组血清IL-6水平明显高于中型、轻型组(P<0.01)。结论:血清IL-6水平增高与脑梗死的发生和严重程度有密切关系。 Objective :To investigate the relations between the serum level of interleukin-6 (IL-6) and the severity of acute cerebral infarction. Methods:The serum level of IL-6 in 63 patients with acute cerebral infarction and 24 healthy persons was determined. All the patients were scored by clinic neurological function deficit scale ( NDS ) , and comparision was made between the groups. Results: The serum level of IL-6 of the patients was significantly higher than that of the normal control( P 〈 0.01 ) ,and the serum level of IL-6 of the group with serious cerebral infarction was significantly higher than the groups with middle and mild cerebral infarction ( P 〈 0.01 ). Conclusious:The serum level of IL-6 is closely correlated with the severity of cerebral infarction.
作者 汪国胜 钟平
出处 《蚌埠医学院学报》 CAS 2008年第3期306-307,共2页 Journal of Bengbu Medical College
关键词 脑梗死 白介素-6 cerebral infarction interleukin-6
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