摘要
通过对我科20年来16种化疗减毒增效药新药临床试验中临床疗效指标设置、试验数据及统计分析结果的回顾性分析,探讨新药临床试验疗效评价中疗效指标的特点、不足和变化趋势,分析并提出进一步完善肿瘤化疗辅助中药新药疗效评价指标和体系的几点建议。
This paper reviews clinical practices of 16 new herbal medicines which can enhance efficacy and reduce toxicity in chemotherapy in the last 20 years in our department. It summarizes the setting up of parameters for curative effects, data and results, and analyzes the characteristics, inadequacy and changing trend of parameters for curative effects in clinical practice. The paper also gives advice on improving the parameters for curative effects of new TCM drugs together with chemotherapy.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2008年第10期821-824,共4页
Chinese Journal of New Drugs
基金
国家科技部863计划:临床试验关键技术及平台研究/肿瘤糖尿病等疾病创新中药的临床试验关键技术及平台研究(2003AA2Z3412)
关键词
肿瘤
中药新药
减毒增效
疗效评价指标
生活质量
tumor
new drugs of Chinese Materia Medica
efficacy enhancing and toxicity reducing
curative effect evaluation target
quality of life
