摘要
目的探讨炮制工艺(白酒与黄酒炮制)对丹参、大黄活血祛瘀作用的影响。方法采用肾上腺素致怒及寒冷造成大鼠血瘀模型,比较丹参、大黄的炮制品对血液流变学指标及对血小板功能、抗凝血指标的影响。结果丹参各炮制品均有明显的活血作用,酒制大黄、生大黄与白酒都有一定的作用,但生大黄与白酒作用较弱。结论丹参、大黄酒制后药效学作用明显加强。
Objective To study the effects of processed （processing with liquor and rice wine） Radix Salviae Mihiorrhizae and Radix et Rhizoma Rhei on activating blood and dispelling stasis. Methods To make the rat model of blood stasis by using anger induced with injecting adrenaline and coldness. To compare the effect of each processed Radix Salviae Mihiorrhizae and Radix et Rhizoma Rhei on the indexes of hemorheology such as blood viscosity, plasma viscosity and ESR, the platelet functions such as platelet adhesion, platelet aggregation and the anticoagulant functions. Results The pharmacological experiment showed that all processed Radix Salviae Mihiorrhizae had obvious effect of activating blood, raw, Radix et Rhizoma Rhei processing with wine and liquor had certain effect, while raw Radix et Rhizoma Rhei and liquor were weaker. Conclusion After Radix et Rhizoma Rhei and Radix Salviae Mihiorrhizae processed with wine, the efficacy strengthens obviously.
出处
《中国药业》
CAS
2008年第11期13-14,共2页
China Pharmaceuticals
关键词
丹参
大黄
炮制
药效学
Radix Salviae Miltiorrhizae
Radix et Rhizoma Rhei
processing of medicinals
pharmacodynamics
