摘要
[目的]探讨大承气汤对脓毒症患者凝血功能的影响。[方法]将44例无凝血功能障碍的脓毒症患者随机分为两组,对照组给予常规综合治疗,治疗组加用大承气汤鼻饲。分别检测两组患者治疗前及治疗后第1、3和7天的凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(Fg)和血小板(PLT)计数。[结果]两组治疗后PT、TT、APTT均延长,Fg和PLT下降;但治疗组治疗后第7天PT、TT、APTT较对照组短,Fg和PLT较对照组高,与对照组比较差异均有显著性(P<0.05)。[结论]大承气汤对脓毒症患者的凝血功能有保护作用。
[Objective] To investigate the effect of Dachengqi Decoction on blood coagulation in patients with sepsis. [Methods] 44 septic patients with normal blood coagulation were randomly divided into two groups treatment group and control group. Both groups were treated with routine integrationt reatment, and additionally, the treatment group was treated with Dachengqi Decoction nasaltube. Prothrombirtime （PT）, thrombin time （TT）, activated partial thromboplast in time （APTT）, fibrinogen （Fg） and platelet count （PLT） were detected before and 1,3,7 days after treatment in the two groups. [Results]At 7 days a{ter treatment in the treatment group,PT, TT and APTT all increased, while both Fg and PLT decreased compared to those of the control group （P〈0.05）. [Conclusion]Dachengqi Decoction has a protection on blood coagulation in patients with sepsis.
出处
《浙江中医药大学学报》
CAS
2008年第3期368-369,共2页
Journal of Zhejiang Chinese Medical University
关键词
大承气汤
脓毒症
凝血功能
Dachengqi Decoction sepsis blood coagulation
