摘要
目的:探讨山莨菪碱联合纳洛酮治疗心肺复苏成功后脑复苏的疗效。方法:将42例心肺复苏成功的患者分为对照组(C组)及治疗组(T组)各21例,C组采用常规治疗,T组加用山莨菪碱4mg/(kg·d)静滴,纳洛酮2.0mg静注,6次/d。比较两组格拉斯哥昏迷评分(GCS)、神经功能缺损评分(NFI)及日常生活活动能力评分。结果:T组在心肺复苏后7d的GCS分值明显高于C组,复苏后2月及3月,NFI评分T组明显低于C组,T组日常生活活动能力分值明显高于C组,P均<0.05。结论:山莨菪碱与纳洛酮合用可有效地改善心肺脑复苏后患者的神经功能状况及提高患者的生活质量。
Objective： To explore the effect of Naloxon and Anisedamine on patients after cardiopulmonary resuscitation （CPR）. Methods： The patients under cardiopulmonary arrest were divided into control group （group C, n= 21） and treatment group （group T, n=21） in randomly. The patients in group T were treated with Naloxone （12 mg/d） and Anisodamine 4 mg/（kg.d）, those in the group C treated by routine method. The questionnaires of glasgow coma scale （GCS）, neurological functional insufficiency （NFI）, general quality of life inventory were compared between two groups. Results： 7 days after CPR, score of GCS in group T was higher than group C, 2 months and 3 months after CPR, score of NFI was lower than group C and scores of quality of life in physical health and cognitive function was also higher than group C,all P 〈 0.05. Conclusion： Combining Naloxon and Anisodamine can improve neurological functional status and the quality of life after CPR efficiently.
出处
《岭南急诊医学杂志》
2008年第2期87-88,97,共3页
Lingnan Journal of Emergency Medicine
关键词
心肺脑复苏
神经功能状况
山莨菪碱
纳洛酮
cardiopulmonary resuscitation
neurological functional status
Naloxon
Anisedamine
