摘要
目的了解2006年8月-2007年8月黑龙江省医院老年呼吸内科下呼吸道感染住院患者病原菌分布及耐药性分析。方法对老年呼吸内科病房下呼吸道感染住院患者痰菌培养阳性标本进行回顾性分析。结果革兰阴性杆菌占79.8%,依次为肺炎克雷伯菌、铜绿假单胞菌、不动杆菌属、阴沟肠杆菌、大肠埃希菌,革兰阳性菌占15.2%,真菌占6.0%;革兰阴性杆菌对亚胺培南、头孢哌酮/舒巴坦、阿米卡星较敏感,革兰阳性菌对万古霉素、呋喃妥因、头孢唑林、亚胺培南较敏感。结论老年呼吸内科下呼吸道感染病原菌,主要为革兰阴性杆菌,以条件致病菌为主,对抗菌药物产生了不同程度的耐药,临床应合理使用抗菌药物,以延缓病原菌耐药的产生。
OBJECTIVE To investigate the distribution and resistance of pathogenic becteria isolated from inpatients with lower respiratory tract infection in Department of Gerontal Respiratory Medicine during from Aug 2006 to Aug 2007. METHODS All the clinical isolates from sputum were analyzed retrospectively. RESULTS There were 211 （79.8 % ） strains of Gram-negative bacilli, 40 （ 15.2% ） strains of Gram-positive bacteria and 12 （ 6 % ） strains of fungi. The most important Gram-negative pathogens were Klebsiella pneumoniae. Pseudomonas aeruginosa, Enterobacter cloacae and Escherichia coli. Strains of Gram-negative bacteria were susceptible to imipenem, cefoperzone/sulbactam and amikacin, strains of Gram-positive pathogens were susceptible to vancomycin, nitrofurantoin, cefazolin and imipenem. CONCLUSIONS Gram-negative bacilli are the major pathogens in lower respiratory tract infection in Department of Gerontal Respiratory Medicine and the dominant is conditional pathogen. Rational use of antibiotics is important for the containment of bacterial resistance.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2008年第5期722-723,746,共3页
Chinese Journal of Nosocomiology
关键词
下呼吸道感染
病原菌
抗菌药物
耐药性
Lower respiratory tract infection
Pathogenic bacteria
Antibiotic
Resistance
