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心力衰竭患者血浆B型尿钠肽水平与D-二聚体的相关性分析 被引量：2

Correlation between B-type natriuretic peptide and D-dimer in patients with heart failure
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摘要 目的探讨冠心病患者心力衰竭时血浆B型尿钠肽(BNP)及D-二聚体(D-D)水平的变化,以及两者的关系。方法检测了79例冠心病心力衰竭患者和20例健康体检者的血浆BNP及D-二聚体水平,并加以比较和作相关性分析。结果冠心病患者心力衰竭时血浆BNP及D-D水平均明显高于对照组(P<0.01),且BNP与D-二聚体水平呈对数正相关(r=0.4398,t=4.2970,P<0.05)。结论冠心病患者心力衰竭时BNP分泌增加,继发性纤溶功能亢进;BNP与D-二聚体两者间存在一定相关性。 Objective To elucidate the correlation between B-type natriuretic peptidc（BNP） and D-dimer in patients with heart failure. Methods BNP, D-dimer were assessed in 79 paients with heart failure and 20 normal controls. Results （1） The serum BNP and D-dimer were higher in patients with heart failure than that in normal controls（P〈0. 001）. （2） There were positive correlation（P〈0. 001）between serum BNP and D-dimer in patients with heart failure. Conclusion （1）The patients with heart failure are abnormal coagulative and fibrinolytic system . （2） BNP is correlated with serum D-dimer and increased in patients with heart failure.
作者 周武 王明山 黄小芳 吕美艳 杨丽红
机构地区 浙江省温州医学院附属第一医院检验科
出处 《重庆医学》 CAS CSCD 2008年第8期858-859,共2页 Chongqing medicine
关键词 心力衰竭 B型尿钠肽 D-二聚体 heart failure B-type natriuretic peptide D-dimer
分类号 R541.6 [医药卫生—心血管疾病] R446.112 [医药卫生—内科学]
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参考文献8

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二级参考文献6

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共引文献93

同被引文献25

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重庆医学
2008年 第8期

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