摘要
目的探讨腹腔积液患者^18F-脱氧葡萄糖（FDG）PET显像的临床应用价值。方法对14例腹腔积液患者的^18F-FDGPET显像资料进行回顾性分析，随访其最终的病理检查结果、生存期等，并将^18F-FDGPET显像资料和随访结果进行比较。用SAS6．12软件进行统计学处理。结果^18F-FDGPET显像发现腹腔积液由恶性肿瘤引起者5例，良性病变引起者6例，假阳性1例和假阴性2例。^18F-FDGPET显像对恶性肿瘤引起腹腔积液原发灶的检出灵敏度、特异性、阳性预测值和阴性预测值分别为5／7，6／7，5／6和6／8；^18F-FDGPET显像示阳性者及阴性者其平均生存期分别为8．5（1—36）个月和15．5（3—50）个月，2组间差异有统计学意义（r=4．42，P〈0．05）。结论^18F-FDGPET显像在腹腔积液患者的临床应用中有积极意义，尤其对于恶性腹腔积液原发灶的检出有一定的应用价值；同时，有助于预测腹腔积液阳性显像患者的生存期。
Objective The aim of this study was to evaluate the clinical value of ^18F-fluorodeoxyglucose （FDG） PET imaging for ascites. Methods Fourteen patients with ascites were included in this retrospective study. The gold standard of ascites was either cytology or clinical follow-up and compared to the PET findings. Data were analyzed with SAS 6.12. Results Of the 14 patients, seven were malignant and seven were benign ascites. The sensitivity, specificity, positive predictive value and negative predictive value of PET were 5/7, 6/7, 5/6, 6/8 respectively. A longer survival was observed in benign than malignant ascites patients （ 1 to 36 months vs 3 to 50 months, χ2 = 4. 42, P 〈 0.05 ）. Condusions ^18F-FDG PET was helpful in predicting malignant from benign ascites. Patients with benign ascites could have longer survivals than with malignant ascites.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2008年第2期108-110,共3页
Chinese Journal of Nuclear Medicine
