摘要
[目的]通过对晚期肺癌化疗期间服用补中益气汤后的临床观察,评价补中益气汤在减少化疗毒副反应,提高生活质量方面的作用。[方法]将46例晚期肺癌患者随机分为治疗组和对照组各23例。两组病例根据肺癌病理分类采用NP或EP化疗方案;治疗组在每个周期化疗前3d开始服用补中益气汤。3个化疗周期结束后比较两组毒副反应发生率及体力状况Karnofsky评分变化,进行统计学分析。[结果]3个化疗周期后治疗组的毒副反应发生率低于对照组,两组之间差异有统计学意义(P<0.05);治疗组Karnofsky评分改善率优于对照组,两组之间差异有统计学意义(P<0.05)。[结论]补中益气汤能减少晚期肺癌化疗后带来的诸多毒副反应,提高患者的生活质量。
[Objective]To evaluate Buzhong Yiqi Decoction＇s functions of reducing toxic and side effects of chemo-therapy, as well as improving life quality,by observing its being administered to advanced lung cancer. [Method] Randomly divide 46 cases into treatment group and control one with 23 cases respectively. Both take NP or EP plan according to their pathological types separately,28 days as a course,for 3 courses in succession; the treatment group takes Buzhong Yiqi Decoction 3 days before chemotherapy, 14 days as a course, for 3 courses. The control one only takes chemotherapy to the whole body. Compare their toxic and side effects, also the Karnofsky score of the their strength after 3 chemo-therapy courses, make statistic analysis. [Result] On the rate of toxic and side effects,the treatment group was lower than the control one,with statistical meaning （P〈0.05） ;so was the improvement of Karnofsky score. [Conclusion] Buzhong Yiqi Decoction can decrease many toxic and adverse effects caused by chemo-therapy and improve patients＇ life quality,exerting good function in the comprehensive treatment of advanced lung cancer.
出处
《浙江中医药大学学报》
CAS
2008年第2期220-221,共2页
Journal of Zhejiang Chinese Medical University
关键词
补中益气汤
肺癌
化疗
毒副反应
Buzhong Yiqi Decoction
lung cancer
chemotherapy
toxic and adverse effects
