摘要
研究了以对羟基苯甲酸、乙醇为原料,对甲苯磺酸铜为催化剂,合成对羟基苯甲酸乙酯,并讨论了催化酯化的影响因素,实验结果表明,对甲苯磺酸铜是合成对羟基苯甲酸乙酯的良好催化剂,优化的反应条件为:对羟基苯甲酸用量为0.10 mol,醇酸摩尔比为4∶1,对甲苯磺酸铜用量为2.2 g,回流温度下反应4.0 h,在此实验下酯化率可达94.3%.产品经傅立叶红外光谱仪及熔点仪表征,证实与目标产物完全一致.
The preparation of ethyl p -hydroxybenzoate by the catalytic reaction of p -hydroxybenzoic acid with ethanol by using copper p-toluene sulfonate as a catalyst has been studied. The effect of different factors such as the mole ratio of alcohol to acid, The dosage of catalyst, Reaction time on the yield of ethyl p-hydroxybenzoate were investigated. The experiment results showed that the appropriate reaction conditions were as follows： When the amount of p - hydroxybenzoic acid was 0. 1 0mol, The molar ratio of ethanol to the acid was 4：1 ,The amount of catalyst was 2.2g, Reaction time was 4. Oh at reflux temperature, The esterification yield reached to 94.3%. The product was characterized by FF - IR spectrum and melting point determination. Product is consistent with the target product.
出处
《商丘师范学院学报》
CAS
2008年第3期77-79,共3页
Journal of Shangqiu Normal University
基金
湖南省青年骨干教师培养对象基金(湘教通[2004]252)
湖南省教育厅优秀青年科研基金(06B089)
关键词
对羟基苯甲酸乙酯
对甲苯磺酸铜
催化
酯化反应
ethyl p - hydroxybenzoate
copper p - toluene sulfonate
catalysis
esterification
