摘要
目的研究中医气虚证与食管癌的病理学类型、分化程度、TNM分期等的关系及在食管癌预后评价中的意义。方法230例食管癌患者在手术前进行中医辨证分型,将患者分为有气虚证组与无气虚证组,评价两组食管癌患者的临床表现、辅助检查结果、手术情况、术后病理检查和随访结果等。结果230例食管癌患者中有70例伴有不同程度的气虚证表现,气虚证的发生率为30.4%。气虚证与食管癌的组织学分化程度、淋巴结转移及浸润深度、TNM分期和预后等有关,有气虚证组的患者比无气虚证组患者的分化程度低、淋巴结转移重、浸润深度深、TNM分期晚、预后差(P<0.05)。两组食管癌患者的大体病理类型、组织学类型的差异无统计学意义(P>0.05)。结论气虚证与食管癌的临床症状和病理特征有密切关系,食管癌有气虚证的患者预后较差。
Objective To investigate the relationship between Qi-deficiency syndrome of traditional Chinese medicine and pathological type, differentiation grade, TNM stage and their significance in prognosis of esophageal cancer. Methods The 230 patients with esophageal cancer were observed based on syndrome differentiation of TCM and divided into two groups ： Qi-deficiency syndrome group and non-Qi-deficiency syndrome group. The symptoms, workup, operational information, pathological data and follow-up results of the two groups were evaluated. Results Of the 230 patients, 70 patients had the symptom of Qi-deficiency syndrome, the occurring rate was 30. 4%. There was a significant difference between Qi-deficiency syndrome group and non-Qi-deficiency syndrome group in the differentiation grade, infiltrating depth, lymph node metastasis, TNM stage and prognosis of esophageal cancer （P〈0.05）. Those with Qi-deficiency syndrome had low differentiation grade, deeper infiltration, serious lymph node metastasis, late in TNM stage and poor prognosis of esophageal cancer than those without Qi-deficiency syndrome （P〈0.05）. There was no significant difference between the two groups in the pathological and histological type （P〉0.05）. Conclusion There is close relation between Qi-deficiency syndrome and the clinical and pathological features of esophageal cancer. The prognosis of esophageal cancer patients with Qi-deficiency syndrome is worse.
出处
《中医杂志》
CSCD
北大核心
2008年第3期255-257,共3页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30450008)
深圳市医学重点专科经费资助项目
关键词
食管癌
气虚证
预后
Esophageal cancer
Qi-deficiency syndrome
Prognosis
