摘要
报道了一种应用原子力显微镜(AFM)实现可控纳米定位沉积的探针修饰新方法。采用改进的AFM探针修饰方法—AFM系统控制的自动进针法—替代通常的将探针浸入"墨水"的直接蘸针法,可控制"墨水"吸附在探针的针尖末端,有效避免纳米点制造过程中非定位沉积的干扰。利用该方法修饰的探针可在DNA分子上可控制备氯化铜溶液纳米点阵,这为生物大分子的局部修饰、加工和改造提供有效途径。
In this paper, we present a coating AFM tip method to facilitate the dip-pen nanolithography (DPN) processes. The small amount of ink can be limited to the apex of atomic force microscope (AFM) tip by adjusting AFM operation parameters. With this automatic AFM-engage system overloading ink, usually disturbing imaging and ma- nipulating, can be avoided. Thereby, a uniform nanoarray of CuC12 is constructed on a DNA molecule. The unique technique may provide a novel approach to precisely modify biological molecule at the nano-meter scale.
出处
《核技术》
CAS
CSCD
北大核心
2008年第3期237-240,共4页
Nuclear Techniques
基金
国家自然科学基金(10675160、10674147、10604061)
上海市自然科学基金(06ZR14105)资助