摘要
目的:探讨胸腺肽α1和干扰素联合人乙型肝炎免疫球蛋白对慢性乙型肝炎(CHB)的治疗作用。方法:164例CHB患者随机分为A,B两组各82例,A组采用胸腺肽α1和干扰素联合人乙型肝炎免疫球蛋白,B组单用干扰素,疗程均为6个月。结果:A组中HBsAg、HBeAg、HBV-DNA阴性分别为25,36,42例,而B组中分别为6,25,28例,并且A组中抗HBs为18例,B组中抗HBs为2例,A、B两组相比差异有显著性。结论:胸腺肽α1和干扰素联合人乙型肝炎免疫球蛋白治疗慢性乙型肝炎,疗效可靠。
OBJECTIVE To observe thymosin α1 and interferon combined immune globulin therapy for chronic hepatitis B. METHODS 164 patients with chronic hepatitic B were randomly divided into treatment group A（82 cases） and control group B （82 cases）. Group A was given with thymosin α1 and interferon combied immune globulin. Group B was given with interferon. Course of treatment： six months. RESULTS grouping group A of HBsAg, HBeAg, HBV-DNA 25 cases, 36 cases, 42 cases were negative spectively hut in group B of HBsAg,HBeAg,HBV-DNA 6 cases,25 cases,28 cases were negative and in group A of anti-HBs 18 cases were positive, but in group B of anti-HBs 2 cases were positivity. The difference was significant. CONCLUSION Thymosin α1 and interferon combined immune globulin is reliable in treating the patients with chronic hepatitis B.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2008年第4期286-288,共3页
Chinese Journal of Hospital Pharmacy
