摘要
目的观察七氟醚或丙泊酚麻醉时脑状态指数(CSI)的变化。方法30例腹腔镜手术患者随机均分成七氟醚组(S组)和丙泊酚组(P组)。麻醉诱导:S组吸入2%的七氟醚,每隔1分钟增加1%;P组每隔1分钟重复给予15 mg丙泊酚,直至患者意识消失。记录患者诱导期的CSI数值,并对患者的镇静程度采用警觉/镇静评分(OAA/S)标准评分。结果S组与P组术前CSI基础值差异无统计学意义,随着麻醉的加深,两组的CSI数值均明显下降(P<0.01),至OAA/S 1分时S组与P组的CSI数值较OAA/S 5分时明显下降(P<0.05或P<0.01),S组与P组的CSI与OAA/S的相关系数r分别为0.843和0.812。结论CSI监测可反映七氟醚或丙泊酚麻醉时的麻醉深度。
Objective To investigate the change of cerebral state index（CSI） during anesthesia induction with sevoflurane or propofol. Methods Thirty ASA class Ⅰ or Ⅱ patients scheduled for selective laparoscopic cholecystectomy were randomly divided to two groups with 15 cases each. Anesthesia induction was performed with 2% sevoflurane inhalation in group S or propofol injection in group P（propofol 15 mg injected）, repeatedly until loss of consciousness（LOC）. CSI was recorded and sedation level was evaluated every other minute using the Observer,s Assessment of Alertness/ Sedation（OAA/S） scale. Results Baseline values Of CSI were not significantly different for group S and P, respectively,which were decreasing as anesthesia was deepening （P〈0.01）. The value of CSI at OAA/S=1 was 49.4±9.7 and 60, 8±7.3 for group S and P. OAA/S was correlated well with CSI,Cr was 0. 843 for group S and 0. 812 for group P, respectively. Conclusion The CSI can reflect the depth of anesthesia during anesthesia with propofol or sevoflurane.
出处
《临床麻醉学杂志》
CAS
CSCD
2008年第2期109-111,共3页
Journal of Clinical Anesthesiology
关键词
脑状态指数
七氟醚
丙泊酚
麻醉诱导
Cerebral state index Sevoflurane Propofol
Anaesthesia induction
