摘要
目的观察长托宁、地塞米松预注抑制芬太尼咳嗽反射的有效性。方法选择全麻病人100例,随机分为实验组(Ⅰ组)和对照组(Ⅱ组),每组50例。Ⅰ组病人于芬太尼静注前10min静注长托宁0.5mg、地塞米松5mg,观察两组病人静注分太尼后1min发生反射性咳嗽的例数(发生率)并进行比较。结果Ⅰ组病人发生发射性咳嗽4例(8%);Ⅱ组病人发生反射性咳嗽18例(36%),两组有极显著性差异(P<0.01)。结论长托宁、地塞米松预注能够抑制芬太尼的咳嗽反射。
Objective To observe the effectiveness of pre-injection of penehyclidine and dexamethasone in restraining cough reflex caused by fentanyl. Methods 100 ehosed patients of general anesthesia were randomly divided into experimental group （Group Ⅰ ） and comparison group（Group Ⅱ ） ,50 patients in each group. Patients in group Ⅰ are mainlined 0.5 mg penehyelidine and 5 mg dexamethasone at 10 min before mainlined fentanyl,then the cough reflex eases（incidence） in two groups were observed and compared at 1 min after patients being mainlined fentanyl. Results There were four cough reflex eases（8%） in Group Ⅰ and 18 eases（36%） in Group Ⅱ. The difference between two groups was very significant（P〈 0.01 ）. Conclusion Pre-injection of penehyelidine and dexamethasone can restrain cough reflex caused by fentanyl.
出处
《中国现代医生》
2008年第7期113-114,共2页
China Modern Doctor
关键词
长托宁
地塞米松
芬太尼
咳嗽反射
Penehyelidine
Dexamethasonum
Fentanyl
Cough reflex
