摘要
目的:研究脂蛋白(a)[Lp(a)]水平与中青年患者心肌梗死(MI)发生的关系。方法:对112例中青年MI患者(MI组)、160例非MI的冠心病患者(非MI组)及180例正常人(正常对照组)进行冠状动脉造影,并检查血清Lp(a)浓度。结果:与正常对照组比较,非MI组和MI组LP(a)水平明显增高,而后者更高。3组LP(a)增高率分别是16.7%,34.4%和61.6%;在高LP(a)水平,MI患者占44.8%,而低LP(a)水平,MI患者占14.4%,以上均差异有统计学意义(均P<0.01)。结论:中青年患者MI的发生与Lp(a)水平增高有关。
Objective：To investigate the relationship between serum lipoprotein（a） level and occurrence of myocardial infarction in middle-young patients. Method：There were 112 middle-young patients with myocardial infarction （MI group）, 160 coronary disease patients without MI （non MI group） and 180 normal subjects （control group） underwent coronary arteriography in this study. Plasma concentration of lipoprotein（a） was measured. Result：Compared with control group, the concentrations of lipoprotein（a） were increased significantly in non MI group and MI group, and even higher in the later. The increase rates of lipoprotein （a） were 16. 7%,34.4% and 61.6% in control, non MI, and MI group respectively （P〈0.01）. In the high level of lipoprotein（a）, the percent of MI patients was 44.8% whereas in the low level, it was 14.4%. Conclusion：Occurrence of myocardial infarction in middle-young patients is associated with the increase plasma concentration of lipoprotein（a）.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2008年第1期42-44,共3页
Journal of Clinical Cardiology
关键词
冠状动脉疾病
心肌梗死
脂蛋白(a)
中青年
Coronary disease
Myocardial infarction
Lipoprotein（a）
Middle-young people
