摘要
总结近年来对绿原酸提取工艺的常用方法,探讨了用酸醇回流法提取绿原酸的最佳方法,用均匀设计选取最佳工艺。结果表明,制备金银花提取物以酸醇回流比较好,最佳提取工艺为乙醇浓度80%,pH=5,回流时间0.5h为最佳条件,绿原酸含量较高。乙醇浓度75%,pH=4,回流时间2.0h,所得绿原酸提取率与最佳工艺接近,适合工业生产。
We summed up the common methods of the extraction process of chlorogenic acid in Flos Lonicerare to determine the optimal method of extracting chlorogenie acid with the results ：The extraction process of acid ethanol is optimum. The optimum extraction conditions are g0% ethanol,pH = 5 ,refluxing 0.5h. The content of chlorogenic acid is fairly high. It is close to the optimum extraction condition,that are 75% ethanol, pH = 4, refluxing 2.0h,and it adapt to industry production.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第2期262-264,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
陕西省教育厅产业化培育项目(06JC15)
关键词
金银花
绿原酸
提取
HPLC
优化
Flos Lonicerare
Chlorogenic Acid
Extraction
HPLC
Optimum
