摘要
Objective：To study the Cryptosporidium infection among young children in Anhui province, and to explore the best way to diagnose the disease. Methods： Stool specimens of 1 204 children were collected; oocysts of Cryptosporidium were identified with auramine O- modified staining, acid-fast staining, safranine T and methylene blue staining, and auramine O-modified acid-fast staining. Results： The detectable rate of Cryptosporidium in four stainings were respectively 2.46%, 1.50%, 1.98% and 3.46%, and there was a higher significant difference in the rate between auramine O-modified acid-fast staining and the others（P 〈 0.005）. The detectable rate was significantly lower in urban children（2.14%, 15/684） than in rural ones（5,19%, 27/520）. Boys and girls had similar detectable rate （1.99%, 24/1 204 vs. 1.50%, 18/1 204）. Cryptosporidium infection was usually subclinical, and its major clinical features included benign diarrhea, mild abdominal pain and nausea. Conclusion：Cryptosporidium infection was relatively common in kindergartens and a higher infection rate was found in rural children. As the majority of the Cryptosporidium infections were subclinical, diagnosis is important although difficult.
Objective：To study the Cryptosporidium infection among young children in Anhui province, and to explore the best way to diagnose the disease. Methods： Stool specimens of 1 204 children were collected; oocysts of Cryptosporidium were identified with auramine O- modified staining, acid-fast staining, safranine T and methylene blue staining, and auramine O-modified acid-fast staining. Results： The detectable rate of Cryptosporidium in four stainings were respectively 2.46%, 1.50%, 1.98% and 3.46%, and there was a higher significant difference in the rate between auramine O-modified acid-fast staining and the others（P 〈 0.005）. The detectable rate was significantly lower in urban children（2.14%, 15/684） than in rural ones（5,19%, 27/520）. Boys and girls had similar detectable rate （1.99%, 24/1 204 vs. 1.50%, 18/1 204）. Cryptosporidium infection was usually subclinical, and its major clinical features included benign diarrhea, mild abdominal pain and nausea. Conclusion：Cryptosporidium infection was relatively common in kindergartens and a higher infection rate was found in rural children. As the majority of the Cryptosporidium infections were subclinical, diagnosis is important although difficult.
基金
Natural Science Foundation of Youth of Anhui University of Science & Technology(1999-21)
