摘要
心肌纤维化是病毒性心肌炎向扩张型心肌病转化的重要环节,由心肌胶原代谢失衡引起,近年来基质金属蛋白酶及其组织抑制因子(MMPs/TIMPs)这一胶原降解系统比例失调造成病毒性心肌炎中胶原合成降解代谢紊乱并导致心肌发生纤维化。
Myocardial Fibrosis, caused by the imbalance of collagen metabolism, is crucial for the transformation from viral myocarditis to dilated cardiomyopathy. Recently, it is demonstrated that matrix metalloproteinases and their tissue inhibitors （MMPs/TIMP）, as a collagen degeneration system, are related to the imbalance of collagen metabolism to the formation of myocardial fibrosis.
出处
《中国心血管杂志》
2007年第6期467-469,共3页
Chinese Journal of Cardiovascular Medicine
