6Naoi M, Maruyama W, Akao Y et al. Dopamine-defived endogenous N-methyl-( R)-salsolinol. Its role in Parkinson's disease. Neurotoxicol Teratol, 2002 ;24:579 - 591 被引量:1
7Naoi M, Maruyama W, Akao Y et al. Apoptosis induced by an endogenous neurotoxin, N-methyl (R) salsolinol, in dopamine neurons. Toxicology, 2000 ; 153 : 123 - 141 被引量:1
8Cleeter MW, Cooper JM, Schapira AHV. Irreversible inhibition of mitochondfial complex Ⅰ by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement. J Neurochem, 1992 ;58:786 - 789 被引量:1
9Zang L. Misra HP. EPR kinetic studies of superoxide radicals generated during the autoxidation of 1 -methyl-4-phenyl-2, 3-dihydropyridinium, a bioaetiveated intermediate of Parkinsonian-inducing neurotoxin 1-methyl-4-phenyl-1,2, 3, 6- tetrahydropyridine. J Biol Chem, 1992 ;267:23601 - 23608 被引量:1
10Sandier M, Bonham CS, Hunter KR et al. Tetrahydroisoquinoline alkaloids: in vivo metabolites of L-DOPA in man. Nature, 1973; 241:439 -440 被引量:1
二级参考文献9
1Bossy-Wetzel E,Newmyer D D,Green D R.Mitochondrial cytochrome C release in apoptosis occurs upstream of DEVD-specific caspase activition and independenty of mitochondrial transmembrane depolarization[J].EMBO J,1998,274:1855. 被引量:1
2Conradt B,Horvitz H R.The C.elegans protein EGL-1 is required for prog rammed cell death and interacts with the Bcl-2-like protein CED-9[J].Cell,1998,93:519-529. 被引量:1
3Walkinshaw,Waters C M.Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis[J].Neuroscience,1994,63:975-987. 被引量:1
4Fahn S.The history of Parkinsonism.MOV[J].Disord,1989,4:S2-S10. 被引量:1
5Blum D,Torch S,Nissou M F.Molecular pathways involved in the neurotoxicity of 6-OHDA,dopamine and MPTP:contribution to the apoptotic theory in Parkinson's disease[J].Progress in neurobiology,2001,65:135-172. 被引量:1
6Polymeropoulos M H,Higgins J J,Golbe L I.Mapping of a gene for Parkinson's disease to chromosome 4q21-q23[J].Science,1996,274:1197-1199. 被引量:1
7Schapira A H.Mitochondrial dysfunction in neurodegenerative disorders.Biochim[J].Biophys.Acta,1998,1366:225-233. 被引量:1
8Mizuno Y,Hattori N,Matsumine H.Neurochemical and neurogenetic correlates of Parkinson's disease[J].J Neurochem,1998,71(3):893-902. 被引量:1
9Mochizuki H,Goto K,Mori H,et al.Histochemical detection of apoptosis in Parkinson's disease[J].J Neurol Sci,1996,137:120-123. 被引量:1
1Simonian N A, Coyle J T. Oxidative stress in neurodegenerative disease [ J ]. Annu Rev Pharmacol Toxicol , 1996,36 ( 34 ) :83 - 106. 被引量:1
2Galvani C E, Gunter K K, Gunter T E. Manganese and calcium transport in mitochondria : implications for manganese toxicity [ J ]. Neurotoxicology, 1999,20 (2 - 3 ) :445 - 53. 被引量:1
3Reaney S H, Kwik-Uribe C L, Smith D R. Manganese oxidation state and its implications for toxicity [ J ]. Chem Res Toxicol,2002, 15(9) :1119 -26. 被引量:1
4Aschner M, Shanker G, Erikson K, et al. The uptake of manganese in brain endothelial cultures [ J ]. Neurotoxicology, 2002,23 ( 2 ) : 165 - 8. 被引量:1
5Teitel S, O'Brien J, Brossi A. Alkaloids in mammalian tissues: II. Synthesis of ( + )and ( - ) -1-substituted-6,7-dihydroxy-1,2,3, 4-tetrahydro-isoquinolines[ J]. J Med Chem, 1972,15 ( 8 ) : 845 - 6. 被引量:1
6Naoi M, Maruyama W, Akao Y, et al. Apoptosis induced by an endogenous neurotoxin N-methyl(R) salsolinol, in dopamine neurons [ J ]. Toxicology,2000,153 ( 1-3 ) : 123 - 41. 被引量:1
7Makoto N, Wakako M, Georgy M N. Dopamine-derived salsolinol derivatives as endogenous monoamine oxidase inhibitors: occurrence, metabolism and function in human brains [ J ]. Neurotoxicology,2004,25 (1-2) : 193 - 204. 被引量:1
8Naoi M, Maruyama W, Akao Y, Yi H. Mitochondria determine the survival and death in apoptosis by an endogenous neurotoxin, N-methyl (R)salsolinol, and neuro-protection by propargylamines [ J ]. J Neural Trans, 2002,109 ( 5-6 ) : 607 - 21. 被引量:1
9Maruyama W, Abe T, Tohgi H, et al. A dopaminergic neurotoxin, (R)-N-methylsalsolinol, increases in parkinsonian cerebrospinal fluid [ J ]. Ann Neurol, 1996,40 ( 1 ) : 119 - 22. 被引量:1