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老年人轻度认知功能障碍的研究进展 被引量:2

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摘要 阿尔茨海默病(AD)是一种进行性神经系统变性病,隐性起病,以记忆力和其他认知功能进行性减退为特征。迄今对该病的病因认识不清,最终确诊需依靠尸检病理证实,但此时已经失去了AD早期诊断及治疗的意义,患者、家属及社会均不能从中受益。轻度认知功能损害(mild cognitive impairment,MCI)是介于痴呆和正常衰老间的认知缺损状态,可能是AD的早期阶段,是AD的高危因素,许多纵向研究表明每年大约有10%~15%这类患者会转变为痴呆,其中绝大部分是AD。因此研究和识别MCI的目的在于早期发现和早期干预,以便延缓或阻止痴呆的发生与发展,为老年性痴呆的防治提供一个最佳的治疗时间窗。
作者 刘佳 钟远
出处 《中华医学杂志》 CAS CSCD 北大核心 2008年第3期206-208,共3页 National Medical Journal of China
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