摘要
赤缸Dasyatis akajei(Muller&henle)隶属于软骨鱼纲,下孔总目,鲼形目,魟科,魟属,常栖息于底质为泥沙的深潭中。赤魟肉性昧甘、咸平,有补气之功效。用其熬油,主治小儿疳积。尾刺研末入药,对治疗胃癌、食道癌、肺癌、乳腺炎、咽喉炎、疟疾、牙痛、魟鱼尾刺刺伤均有一定疗效。赤魟尾刺含有多种毒素,有重要药理作用。涂洪斌等克隆出编码赤魟肿瘤抑制因子IPL的全长cDNA序列,并报道了赤魟亲环素A的融合表达、纯化及活性特征。
In vivo antitumor effects of the extracts from caudal spine of Dasyatis akajei by 20% alcoholic and 1% hydrochloride were investigated by testing the tumor weight of tumor-beating mice (S180). The results showed that the extracts of caudal spine of Dasyatis akajei exhibited obvious inhibitory effects on the growth of S180.
出处
《广东海洋大学学报》
CAS
2007年第6期84-85,共2页
Journal of Guangdong Ocean University
基金
广东省重大科技兴海项目(A200099B01)
关键词
赤缸
尾刺
提取物
抗肿瘤作用
Dasyatis akajei
caudal spine
extracts
antitumor activity