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微RNA与肺癌 被引量:6

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摘要 微RNA(miRNA)是一类约22nt的小分子非编码RNA,在转录后水平调控蛋白质的表达。大部分微RNA在基因组上定位于与肿瘤相关的脆性位点上,与肿瘤的发生、发展关系密切。在肺癌组织中,某些微RNA表达水平升高,而某些表达下降,它们充当"癌基因"或者"抑癌基因"的角色,可能在肺癌的诊断、治疗及预后监测中发挥重要作用。
出处 《生命的化学》 CAS CSCD 北大核心 2007年第6期536-538,共3页 Chemistry of Life
基金 国家自然科学基金资助项目(30672076)
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