摘要
目的:探讨VEGF在食管癌中的表达及与肿瘤组织的分化、有无淋巴结转移及肿瘤浸润的关系。方法:收集44例原发性食管癌,20例癌旁组织和20例正常组织,采用免疫组化(SP)方法检测VEGF的表达。结果:VEGF表达在食管癌组织中明显高于其他组织,且与其病理分级、有无淋巴结转移及肿瘤浸润有相关性,P<0.05。结论:VEGF与食管癌病变进展有关,可作为食管癌预后判断的客观指标。
Objective：To investigate expression of VEGF in esophageal carcinoma and its clinical significance. Methods：Immunohis -tochemical staining S-Pmethod was used to detect VEGF expression in normal mucous tissue （20 cases）, in the tissue adjacent to tumor （20cases） and in esophageal carcinoma tissue （44cases）. level in esophageal carcinoma tissue was much higher than those in normal mucous tissue and in the tissue adjacent to tumor. There was significant difference between the three teams（ P 〈 0.05 ）. Conelusion：VEGF is associated with the growth of esophageal carcinoma. VEGF could be considered as an objective predictable index for prognosis of esophageal carcinoma.
出处
《牡丹江医学院学报》
2007年第6期28-29,共2页
Journal of Mudanjiang Medical University
关键词
食管癌
VEGF
免疫组化
Esophageal carcinoma
VEGF
Immunohistochemistry
