摘要
目的探讨影响肺表面活性物质(PS)疗效的因素。方法分治愈组及死亡组总结分析使用肺表面活性物质治疗19例新生儿肺透明膜病的情况。结果使用PS前两组PH、PCO2有显著性差异;孕周、出生体重、出生窒息史、PS剂量有显著性差异。缓慢给药病例与快速给药病例肺出血、脑出血、动脉导管重新开放等并发症有显著性差异。结论早期足量使用PS,使用前注意改善通气、纠正酸中毒,PS注入速度应缓慢,以不少于15分钟为宜。
Objective To illuminate the factors affecting the curative effects of surfactant. Methods 19 in-hospital patients with hyaline membrane disease were allocated into healing group and death group and treated with surfactant. Results significant difference was found on pH and PCO2 between the two groups before treating with surfactant. There were significant difference about pregnant weeks, birth weight, apnea and dosage of surfactant between the two groups. And incidence of complications such as pulmonary hemorrhage, cerebral hemorrhage, pulmonary arterial duct reopening between the slowly instilled and quick instilled cases had significant differences. Conclusions sufficient dosage and early use of surfactant is very necessary. And improvement of ventilation, correction of acidosis before given surfactant and instillation of surfactant no less than 15 minutes is very necessary.
出处
《海南医学》
CAS
2008年第1期50-51,共2页
Hainan Medical Journal
