摘要
目的探讨唇腭裂的遗传及环境致病因素的作用。方法对2245例唇腭裂患者的临床资料进行详细的调查分析。结果单纯唇裂1352例,合并唇腭裂893例。男女性别之比为2.2:1。有遗传史者204例,有服药史者(孕早期)831例。结论唇腭例的病因是复杂的,而遗传因素和母亲孕早期感染、服药、接触毒物等特定环境因素的作用是其致病的危险因素。
Objective To study the effects of hereditary and environmental pathogenic factors on cheilopalatognathus. Methods The clinical data of 2 245 cases with cheilopalatognathus were analyzed. Results Out of 2 245 cases, there were 1352 cases with cheilognathu, and 893 cases with cheilopalatognathus. The ratio between male and female was 2.2： 1. 204 cases had family history of hereditary diseases, and the mothers of 831 cases took medicines during their early pregnancy. Conclusion The pathogenic factors of cheilopalatognathus are very complicated, and the hereditary factors, mother＇s early pregnant infections, taking medicines, contacting narcotics, and other specific environmental factors may be the pathogenic risk factors of cheilopalatognathus.
出处
《兰州大学学报（医学版）》
CAS
2007年第4期29-31,共3页
Journal of Lanzhou University（Medical Sciences）
关键词
唇腭裂
遗传
环境
病因学
cheilopalatognathus
heredity
environment
etiology
