摘要
目的骨转移为乳腺癌的常见转移部位，其最大危害是骨痛，应采用一系列方法减轻骨痛，努力提高患者的生存质量。方法７０例乳腺癌骨转移患者采用化疗、放疗、内分泌、同位素和综合治疗，分单一方法治疗组和综合方法治疗组，观察治疗后疼痛缓解和功能障碍恢复情况，经ｔ检验得出结论。结果单一方法治疗中，内分泌和同位素治疗有效率高于单纯化疗和放疗；单一方法治疗有效率为５６．４％，综合治疗有效率为９０％，经统计学处理，Ｐ＜０．０１。结论单纯内分泌和同位素治疗优于单纯化疗和放疗，乳腺癌骨转移患者雌孕激素受体多为阳性，更适于内分泌治疗；综合治疗明显优于单一治疗，综合治疗中大剂量化疗加内分泌治疗效果最佳。
Objective Bone metastasis is common in breast cancer patients and its main symptom is bone pain. A series of methods were tried to relieve bone pain and to improve quality of life. Methods 70 cases of bone metastases of breast cancer were divided into 2 groups and treated with either chemotherapy, radiotherapy, endocrine therapy or isotope therapy alone or in combination. Results Endocrine therapy or isotope therapy given alone was more responsive than chemotherapy or radiotherapy alone. When the treatment modalities were used comprehensively, the response rate was 90% as compared to 56.4% in patients given single modality treatment ( P <0 01). Conclusion Endocrine or isotope therapy given alone is more effective than chemothrapy or radiotherapy alone. Patients positive for estrogen and progesterone receptors, are more suitable for endocrine therapy. Comprehensive treatment is recommended.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
1997年第4期284-286,共3页
Chinese Journal of Oncology
关键词
乳腺肿瘤
骨肿瘤
综合疗法
肿瘤转移
Breast neoplasms Bone neoplasms/secondary Bone neoplasms/therapy Combined modality therapy
