摘要
目的：探讨用保守方法治疗实验性股骨头坏死。方法：给予类固醇激素，诱导出兔股骨头坏死动物模型，同时使用大蒜素和川芎嗪治疗，然后采用放射性微球技术测量其股骨头血流量。结果：本方法可增加模型动物股骨头血流量，其增加幅度与对照组相比有显著差异（Ｐ＜００５）。结论：川芎嗪和大蒜素与类固醇激素同时应用可预防股骨头坏死的发生，并对已发生的早期股骨头坏死有一定的治疗作用。
Objective:To study conservative treatment of experimental femoral head necrosis.Method:On the basis of successfuly induced rabbit models of femoral head necrosis,using Lingustrazine and Garlicin to treat the rabbits,and then,bone blood flow of femoral head was measured with radioactive microsphere technique.Result: Lingustrazine and Garlicin given at the same time immediately or 4 weeks after establishment the model,could signifignantly increase bone blood flow( P< 0 05).Conclusion: Lingustrazine and Garlicin may prevent steroid induced femoral head necrosis,and have good effect on early stage of the necrosis of femoral head.
出处
《中日友好医院学报》
1997年第2期109-112,共4页
Journal of China-Japan Friendship Hospital
基金
卫生部科研基金
关键词
股骨头坏死
放射性微球技术
药物疗法
中药
rabbits
femur head necrosis
radioactive microsphere technique
drugs,Chinese herbal
