摘要
目的观察中心性浆液性脉络膜视网膜病变（CSC）眼底自身荧光（AF）的影像特征。方法采用海德堡激光扫描眼底造影系统和Kowa眼底彩色照相系统，对72例CSC患者的85只患眼进行眼底彩色照相、无赤光照相、荧光素眼底血管造影（FFA）检查，使用488nm波长激光获取灰白的AF图像并与眼底彩色照相、无赤光照相及FFA图像进行对比分析。结果85只患眼中，CSC病灶AF表现为单发的弱AFl2例14只眼，占16．5％；弱AF中包含较弥漫的强AF病灶32例39只眼。占45．9％；弱AF和斑点状AF相连的复合病灶22例25只眼，占29．4％；后极部局部斑点状密集或散在强弱AF5例7只眼，占8．2％。FFA荧光素渗漏点或异常荧光与异常AF相对应者54例60只眼，占70．6％；眼底改变和FFA、眼底AF变化不一致者18例25只眼，占29．4％。不同病程的CSC病灶AF表现不一，发病期表现为单发的盘状弱AF池，以及弱AF池内或外斑点状强AF复合病灶；慢性迁延期可见斑点状强弱AF交织，范围大小不等的多发病灶。结论CSC的AF以单发的弱AF池、强弱AF交织的复合病灶以及黄斑区AF多发病灶多见；AF检查结合眼底彩色照相、FFA检查，可以对CSC的影像观察起到相互补充的作用。
Objective To observe the image characteristics of autofluorescence （AF） in central serous chorioretinopathy （CSC）. Methods A total of 85 eyes of 72 patients with CSC were examined by Headberg HRA-2 laser scanning fundus fluorescein angiography （FFA）, red-free light photography, and Kowa fundus colorized photography. The grey AF images were obtained with 488 nm wave length laser and comparatively analyzed with results of fundus colorized photography, red-free light photography and FFA. Results In 85 eyes, single faint AF of the CSC focus was in 14 （16. 5%）; faint AF pool containing strong lamellar focus was in 39 （45.9%） ; faint AF pool combining with mottling focus was in 25 （29.4%） ; local dense or scattered mottling AF at the posterior pole was in 7 （8.2%）. FFA fluorescein leakage point or abnormal fluorescence were in accordance with abnormal AF in 60 eyes （70. 6%）; the changes of ocular fundus, results of FFA, and changes of AF were not accordance in 25 eyes （29.4 % ）. AF of CSC focus during different disease course was different, which showed single plate like faint AF pool and strong mottling AF complex focus in and out of the faint AF in the period of onset of the disease, while strong mottling combining with faint mottling AF and various multi infection fields in the period of chronicity. Conclusions The AF of CSC mainly demonstrates single faint AF, strong mottling combining with faint mottling AF and multi-infection AF in macular fields. AF examination associates with fundus colorized photography and FFA can be mutually complemented in observing the images of CSC.
出处
《中华眼底病杂志》
CAS
CSCD
北大核心
2007年第6期384-387,共4页
Chinese Journal of Ocular Fundus Diseases
关键词
荧光
荧光素血管造影术
视网膜疾病
Fluorescence
Fluorescein angiography
Retinal diseases
