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C-反应蛋白与急性下肢深静脉血栓炎症反应的研究 被引量:12

Relationship between C-reactive protein and acute lower limb deep vein thrombosis inflammatory response
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摘要 目的:探讨急性炎症因子C-反应蛋白(C-reactive protein,CRP)和炎症细胞在急性下肢深静脉血栓(deep vein thrombosis,DVT)形成中的作用。方法:比较急性下肢DVT患者(DVT组)和健康志愿者(对照组)的血浆CRP水平、外周血白细胞、中性粒细胞、单核细胞及淋巴细胞计数。结果:DVT组血清CRP水平明显高于对照组(n=30,P<0.01),白细胞、中性粒细胞和单核细胞计数显著高于对照组(n=30,P均<0.001);而淋巴细胞计数两组间差异无统计学意义(n=30,P>0.05)。结论:下肢DVT与急性炎症因子和炎症细胞相互影响,CRP可能成为评价DVT预后的指标之一。 Objective:Investigate the effect of C-reactive protein and inflammatory factors in lower limb deep vein thrombosis. Method: Fifteen patients and 15 volunteers (control) were included. C-reactive protein and leucocytes, neutrophil, monocytes and lymphocytes in serum were dectected.Results:The C-reactive protein washigher in DVT than control(n=30, P〈0.01) ,the leucocytes, neutrophil, monocytes were higher in DVT than control(n=30, P〈0.001). However,, there is no difference of the lymohocytes between DVT and control (n=30, P〉0.05).Conclusion:CRP and inflammatory cell might play an important role in thrombosis.
出处 《中国现代普通外科进展》 CAS 2007年第5期398-400,共3页 Chinese Journal of Current Advances in General Surgery
关键词 C-反应蛋白·深静脉血栓·炎症 C-reactive protein · Deep vein thrombosis · Inflammatory
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