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等容稀释加多巴酚丁胺和胞二磷胆碱治疗脑血管痉挛的研究

Study on Cerebral Vasospasm with Isovolemic Hemodilution and Dobutamine and Cytidine Disphisphate Choline (CDPC)
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摘要 目的:寻找一种有效的治疗脑血管痉挛的新方法。方法:蛛网膜下腔出血(SAH)后所致的症状性脑血管痉挛(CVS)病人16例,采用等容稀释加多巴酚丁胺和胞二磷胆碱进行治疗。结果:治疗后脑电和CT检查正常。基底动脉TCD血流速度和心输出量分别由治疗前的51±13.6cm/s和4.60±1.6L/min增加到治疗后的70±12.6cm/s和11.5±2.86L/min(P<0.05)。除两例肢体肌力由原来的Ⅲ级恢复到Ⅳ级外,其余均恢复正常。总有效率高达94%。结论:该法治疗CVS有效。 Objective:To find an effective method of treating cerebral vasospasm.Methods:Sixteen cases with symptomatic vasospasm after SAH were treated with isovolemic hemodilution and dobutamine and CDPC.Results:EEG and CT examination was normal after treating.Blood veloctities of basilar artery TCD (70±12 6 cm/s) in patients treated with this method and cardiac output (11 5±2 86 L/min) were higher than those (51±13 6 cm/s and 4 60±1 61 L/min respectively) in patients without treating (P<0 05).Myodynamia also returned to normal besides 2 patients.The cure rate was 94%.Conclusions:Patients who suffered from cerebral vasospasm could be treated with this method.
出处 《中国冶金工业医学杂志》 1997年第2期79-80,共2页 Chinese Medical Journal of Metallurgical industry
关键词 蛛网膜下腔出血 多巴酚丁胺 胞二磷胆碱 SAH Cerebral vasospasm Isovolemic hemodilution Dobutamine CDPC
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